Yoram Reiter, PhD, Professor

Molecular Immunology Lab

Molecular Immunology lab, which focuses on the bridge between basic and translational research in the fields of immunotherapy of cancer and autoimmune diseases. We study basic mechanisms of T cell function and regulation with emphasis on T cells engineered with chimeric antigens receptors (CAR-T cells) or T cell receptors (TCRs).

We are employing antibody-engineering approaches to generate and study novel antibodies that target the intracellular proteome as novel means to device new therapeutic strategies in the forms of CAR-T cells, bi-specific antibodies, and T cell engagers for oncology and autoimmune indications as well as using them as a tool to elucidate basic machineries of T cell function and regulation.

Our lab combines state of the art research in molecular immunology, molecular biology, antibody and T cell engineering, systems immunology as well as interdisciplinary approaches that combine computational approaches for target discovery as well as mathematical models for understanding function and regulation of immune cells.