RESEARCH

"Sarcoma 0-40"

Sarcoma 0-40 Initiative

"Sarcoma 0-40"

Understanding and treating sarcomas and mesenchymal tumors remain major challenges in cancer research and represent an unmet clinical need. To make a significant impact on sarcomas affecting children and young adults, the RTICC (Technion) has joined forces with the Case Comprehensive Cancer Center (CCCC) at Case Western Reserve University in Cleveland and the Department of Pediatrics at the Indiana University School of Medicine. Together, we have established an international, multi-center consortium termed “Sarcoma 0–40,” which focuses primarily on Ewing sarcoma and osteosarcoma in pediatric and young adult populations.

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"Sarcoma 0-40" Call for Proposals

To make a significant impact on sarcomas in children and young adults, the RTICC (Technion) joined forces with the Case Comprehensive Cancer Center (CCCC) at Case Western Reserve University in Cleveland and the Department of Pediatrics at Indiana University School of Medicine to establish an international multicenter initiative called "Sarcoma 0-40."
We invite Faculty members of the RTICC, CCCC, and Department of Pediatrics at Indiana University School of Medicine to apply for the collaborative joint grants.
The funding will foster synergy between partner institutions (at least two, with the RTICC being one of them at this stage) by combining their complementary expertise, while offering co-mentoring to students, post-doctoral or clinical fellows, as well as hands-on experience in both laboratories.

Submission Deadline: April 30th, 2026

"Sarcoma 0-40" Researchers

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Indiana University, School of Medicine, Department of Pediatrics

Wade Clapp

Prof. Wade Clapp, MD

Use of Proteomics and Preclinical Models Identify Molecular Vulnerabilities of NF1 PNSTs

karen pollock

Prof. Karen E. Pollok

Precision Genomics& Preclinical Modeling

Pankita H. Pandya

Asst. Prof. Pankita H. Pandya

Precision Genomics& Preclinical Modeling

Ed Greenfield

Prof. Ed Greenfield

Osteosarcoma

Chris Collier

Asst. Prof. Chris Collier, MD

Understanding the Intersection of Orthopaedics and Cancer

Brian D Weiss

Prof. Brian D Weiss, MD

Division Chief for Pediatric Hematology/Oncology/Stem Cell Transplant

Kyle Jackson

Asst. Prof. Kyle Jackson

The Biology of Underlying Pediatric Bone Sarcomas

Marissa Just

Dr. Marissa Just

Soft Tissue Sarcomas, Rhabdomyosarcoma

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Case Comprehensive Cancer Center, Case Western Reserve University

Gary Schwartz

Prof. Gary Schwartz, MD

Citruvivint and Ewing Sarcoma

Berkley Gryder

Asst. Prof. Berkley Gryder

Epigenetics & 3D Genomics, Drug Discovery & Development

Alex Y. Huang

Asst. Prof. Alex Y. Huang, MD, PhD

Cellular & Molecular Immunology & Tumor Immunity

Reshmi Parameswaran

Assoc. Prof. Reshmi Parameswaran

OSM CAR-T Therapy for Sarcomas

Rebecca Obeng

Asst. Prof. Rebecca Obeng, MD, PhD, MPH

Therapeutic Remodeling the Tumor Immune Microenvironment

Seth Corey

Prof. Seth Corey

Animal Models, Ewing Sarcoma

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RTICC Rappaport Cancer Research Center, Technion-Israel Institute of Technology

Prof. Amir Orian | RTICC Director

Prof. Amir Orian, MD, PhD

RNF4-LOX axis in Sarcoma

Peleg Hasson

Prof. Peleg Hasson

Tissue Development & Regeneration

Dr. Oz Mordechai, Rambam Health Care Campus

Dr. Oz Mordechai, MD

Pediatric Sarcoma, genetics, precision medicine, and immuno-oncology

Prof. Aaron Ciechanover, Rappaport Faculty of Medicine, All rights Reserved to the Technion- Israel Institute of Technology

Distinguished Prof. Aaron Ciechanover

Ubiquitin-related Therapy in Sarcoma

Dana Ashkenazi Lustig

Dr. Dana Ashkenazi Lustig, MD

From Rare Pediatric Cancers to Precision Nanotherapy

Prof. Yossi Shamay

Assoc. Prof. Yosi Shamay

Cancer Nanomedicine and Nanoinformatics

Myriam Ben Arush

Prof. Myriam Ben Arush, MD

Rhabdomyosarcoma and new drugs in pediatric sarcomas

Prof. Shenhav Shemer, Faculty of Biology

Assoc. Prof. Shenhav Shemer

Biomarkers and pathways of muscle atrophy

David Nikomarov

Dr. David Nikomarov, MD

Director of Orthopedic Oncology Surgery at Rambam Medical Center.

Rostislav Novak

Dr. Rostislav Novak, MD

Role of LOX proteins in TME remodeling and metastatic progression

Prof. Yuval Shaked, Rappaport Faculty of Medicine

Prof. Yuval Shaked

Host response to therapy

Prof. Moti Freiman, Faculty of Biomedical Engineering

Assoc. Prof. Moti Freiman

AI-enabled quantitative MRI for Sarcoma management

Prof. Hadar Zigdon-Giladi, Rambam Health Care Campus

Prof. Hadar Zigdon-Giladi, MD

Structural and mechanical alterations in the bone microenvironment

Or-Yam Revach

Or-Yam Revach, PhD

Tumor Immunology and Immunotherapy

Prof. Alejandro Sosnik, Faculty of Materials Science and Engineering

Prof. Alejandro Sosnik

Novel hybrid nanomaterials for targeted sonodynamic therapy

Prof. Israel Vlodavsky, Rappaport Faculty of Medicine

Prof. Israel Vlodavsky

role of Hpa2 in sarcoma