Yehuda Assaraf, PhD, Professor

Intrinsic and acquired resistance to chemotherapeutic agents remains a major impediment towards curative cancer therapy of various human malignancies.

Hence, research in our lab focuses on deciphering the molecular mechanisms underlying anticancer drug resistance in cultured tumor cells as well as unravelling the molecular basis of chemoresistance in individual cancer patients. Based on the discovery of such mechanisms, we are developing novel strategies to overcome well-defined modalities of anticancer drug resistance that will pave the way towards efficacious personalized medicine.